Imikhiqizo

Izakhiwo zomzimba nezamakhemikhali ze-threonine

Ukubukeka: impushana emhlophe

Uhlolojikelele

I-L-threonine iyi-amino acid ebalulekile, futhi i-threonine isetshenziswa kakhulu kwezokwelapha, ama-reagents amakhemikhali, iziqinisi zokudla, izithasiselo zokudla, njll. Ikakhulukazi, inani lezithako zokudla liye lakhula ngokushesha.Ivamise ukungezwa ekuphakeleni kwamaphuphu amancane nezinkukhu, futhi iyi-amino acid ekhawulelayo yesibili ekudleni kwezingulube kanye neyesithathu ekhawulela i-amino acid ekudleni kwezinkukhu.Ukwengeza i-L-threonine kokuphakelayo okuhlanganisiwe kunezici ezilandelayo: ① Kungalungisa ibhalansi ye-amino acid yesiphakeli futhi kukhuthaze ukukhula kwemfuyo;② Ingathuthukisa ikhwalithi yenyama;③ Ingathuthukisa inani lokudla okuphakelayo ngokugayeka kokudla kalula kwe-amino acid;④ Kunganciphisa Izindleko feed impahla eluhlaza;ngakho-ke, isetshenziswe kabanzi embonini yokudla emazweni e-EU (ikakhulukazi iJalimane, iBelgium, iDenmark, njll.) kanye namazwe aseMelika.

Zitholele

Yahlukaniswa futhi ikhonjwa ku-fibrin hydrolyzate yi-WCRose1935.Ngo-1936, u-Meger wafunda ukwakheka kwayo kwendawo futhi wayiqamba ngokuthi i-threonine ngenxa yesakhiwo sayo esifanayo ne-threose.Kukhona ama-isomers amane e-threonine, futhi i-L-threonine iyona eyenzeka ngokwemvelo futhi inemiphumela yomzimba emzimbeni.

indlela ye-metabolic

Indlela ye-metabolic ye-threonine emzimbeni ihlukile kwamanye ama-amino acid.Yiyo yodwa engayitholi i-dehydrogenase ne-transamination, kodwa nge-threonine dehydratase (TDH) kanye ne-threonine dehydration (TDG) kanye ne-aldehyde condensation.Ama-amino acid aguqulwa abe ezinye izinto ezikhiqizwa ama-enzyme.Kunezindlela ezintathu eziyinhloko: i-metabolized ku-glycine ne-acetaldehyde nge-aldolase;i-metabolized ku-aminopropionic acid, i-glycine, ne-acetyl COA nge-TDG;i-metabolized to propionic acid kanye ne-α-aminobutyric acid nge-TDH

Ukusetshenziswa komkhiqizo we-Threonine

Inhloso eyinhloko

I-Threonine iyisiqiniseko esibalulekile somsoco, esingaqinisa okusanhlamvu, amakhekhe, kanye nemikhiqizo yobisi.Njenge-tryptophan, ingakhulula ukukhathala komuntu futhi ikhuthaze ukukhula nokuthuthuka.Emithi, ngenxa yokuthi isakhiwo se-threonine siqukethe amaqembu e-hydroxyl, sinomthelela wokubamba amanzi esikhumbeni somuntu, esihlangene namaketanga e-oligosaccharide, sidlala indima ebalulekile ekuvikeleni ulwelwesi lwamangqamuzana, futhi lungakhuthaza ukuhlanganiswa kwe-phospholipid kanye ne-fatty acid oxidation emzimbeni.Ukulungiswa kunomphumela wokwelapha wokugqugquzela ukuthuthukiswa komuntu kanye nokumelana nesibindi esinamafutha, futhi kuyingxenye ye-compound amino acid infusion.Ngesikhathi esifanayo, i-threonine iphinde ibe yimpahla eluhlaza yokwakhiwa kwekilasi lemithi elwa namagciwane esebenza kahle kakhulu ne-hypoallergenic, i-monoamidocin.

Imithombo yokudla eyinhloko: ukudla okuvutshiwe (imikhiqizo yokusanhlamvu), amaqanda, i-chrysanthemum, ubisi, amantongomane, irayisi, izaqathe, imifino enamahlamvu, i-papaya, i-alfalfa, njll.

I-Threonine isetshenziswa kwezokwelapha, ama-reagents amakhemikhali, iziqinisi zokudla, izithasiselo zokudla, njll. Ikakhulukazi, inani lezithako zokudla liye lakhula ngokushesha.Ivamise ukungezwa ekuphakeleni kwamaphuphu amancane nezinkukhu, futhi iyi-amino acid ekhawulelayo yesibili ekudleni kwezingulube kanye neyesithathu ekhawulela i-amino acid ekudleni kwezinkukhu.[4]

Ngokuthuthuka kwezinga lokuphila kwabantu kanye nokuthuthukiswa kwe-aquaculture, i-threonine, njenge-amino acid yokudla, isetshenziswa kakhulu ukwengeza ukudla kwezingulube, ukuzalanisa ukudla kwezingulube, ukudla kwe-broiler, ukudla kwezimfanzi kanye nokudla kwe-eel.Inezici ezilandelayo:

——Lungisa ibhalansi ye-amino acid emfundweni ukuze kuthuthukiswe ukukhula;

- ingathuthukisa ikhwalithi yenyama;

- ingathuthukisa inani lokudla okunempilo kwezithako zokudla ngokugayeka kokudla okuphansi kwe-amino acid;

——Ingakhiqiza ukudla okunamaphrotheni aphansi, okusiza ukulondoloza imithombo yamaprotheni;

——Kunganciphisa izindleko zempahla yokuphakelayo;

——Inganciphisa okuqukethwe kwe-nitrogen emfuyweni nasemfuyweni wezinkukhu kanye nomchamo, kanye nokugxila kwe-ammonia kanye nezinga lokukhululwa ezindlini zemfuyo nezinkukhu.

Njengamanje, ososayensi baseJalimane bathole i-threonine egazini lomuntu, futhi ucwaningo luye lwathola ukuthi ingavimbela i-HIV ekuxhumeni nasekuhlaseleni amaseli e-somatic, ngokuphazamisa iphrotheni engaphezulu ye-HIV, iyenze ingakwazi ukusebenza.Ukutholakala kwale amino acid kunikeza indlela yokwakhiwa kwemithi elwa nengculazi.

Isidingo sohlelo lokusebenza ukondla

Okwamanje, ukushoda kwezinsiza zokudla, ikakhulukazi ukuntuleka kokudla okunamaphrotheni okufana nempuphu yesoya kanye nokudla kwenhlanzi, kukhinyabeza kakhulu ukuthuthukiswa kokufuywa.I-Threonine ivamise ukuba yi-amino acid yesibili noma yesithathu enciphisa ukudla kwengulube, kanti eyesithathu noma yesine ekhawulela i-amino acid ekudleni kwezinkukhu.Ngokusetshenziswa okubanzi kwemikhiqizo yokwenziwa ye-lysine ne-methionine ekudleni okuyinhlanganisela, kancane kancane Sekuyisici esinqunyelwe esithinta ukusebenza kwemfuyo nezinkukhu, ikakhulukazi ngemuva kokwengeza i-lysine ekudleni okune-protein ephansi, i-threonine isibe yi-amino acid yokuqala ekhawulelayo. ezingulubeni ezikhulayo.

Uma i-threonine ingasetshenziswa ekuphakeleni, ukulawulwa kwe-threonine ekudleni kungathembela kuphela ezintweni ezingavuthiwe zamaprotheni, futhi izinto zokusetshenziswa zamaprotheni aziqukethe kuphela i-threonine, kodwa futhi namanye ama-amino acid abalulekile futhi angabalulekile.Umphumela wokusebenzisa i-threonine ukulungisa ibhalansi ye-amino acid ukuthi ibhalansi ye-amino acid yesiphakeli ayikwazi ukuthuthukiswa ngangokunokwenzeka, ukumoshakala kwenani elikhulu lama-amino acid abalulekile ngeke kuncishiswe ngokuqhubekayo, futhi izindleko zefomula yokudla. ayikwazi ukuncishiswa ngokuqhubekayo.Umkhawulo okufanele weqe ukuze kuthuthukiswe ibhalansi ye-amino acid inkinga yebhodlela bonke abaklami abangakwazi ukuyigwema.

Ukusetshenziswa kwe-threonine kunganciphisa ukumoshakala kwama-amino acid abalulekile nangabalulekile, noma kunciphise izinga leprotheyini elingahluziwe lokuphakelayo.Isizathu siyefana nokusebenzisa i-lysine hydrochloride.Izinga leprotheyini elingahluziwe lokuphakelayo lingatholakala ngokusebenzisa ama-amino acid ayikristale.Ukunciphisa okunengqondo, ukusebenza kokukhiqizwa kwezilwane ngeke konakaliswe, kodwa kungase kuthuthukiswe.