Imikhiqizo

I-Losartan umuthi ongokwesigaba sezidakamizwa ezaziwa ngokuthi ama-angiotensin II receptor blockers (ARBs).Ngokuyinhloko isetshenziselwa ukwelapha umfutho wegazi ophakeme (umfutho wegazi ophezulu) kanye nezinhlobo ezithile zezimo zenhliziyo.I-Hypertension yisimo esivamile esibonakala ngamazinga aphezulu omfutho wegazi.Uma ingelashwa, ingaholela ezinkingeni ezinkulu zempilo njengesifo senhliziyo, unhlangothi, nezinkinga zezinso.I-Losartan isebenza ngokuvimbela ukusebenza kwehomoni ebizwa ngokuthi i-angiotensin II, ebopha imithambo yegazi futhi ibangele ukukhuphuka komfutho wegazi.Ngokuvimbela le hormone, i-losartan isiza ukuphumula nokwandisa imithwalo yegazi, ngaleyo ndlela inciphise ukucindezeleka kwegazi.Ngaphezu kokwelapha umfutho wegazi ophezulu, i-losartan nayo inenzuzo ezimweni ezithile zenhliziyo, njengokuhluleka kwenhliziyo kanye ne-left ventricular hypertrophy.Ingasiza ekuthuthukiseni izimpawu, ithuthukise ukusebenza kwenhliziyo, futhi inciphise ingozi yezenzakalo zenhliziyo nemithambo yegazi ezigulini ezinalezi zimo.Ngaphezu kwalokho, i-losartan itholakale inomphumela wokuvikela izinso kubantu abanesifo sikashukela sohlobo lwe-2 kanye ne-nephropathy yesifo sikashukela (isifo sezinso).Inganciphisa ukuqhubeka kokulimala kwezinso, yehlise i-proteinuria (amaprotheni amaningi emchamweni), futhi isize ukugcina ukusebenza kwezinso kulaba bantu.Umthamo nokusetshenziswa kwe-losartan kungase kwehluke kuye ngesimo somuntu, ubudala, nezinye izici.Ngokuvamile kuthathwa ngomlomo kanye ngosuku, ngokudla noma ngaphandle kokudla.Kubalulekile ukulandela umthamo onqunyiwe kanye nemiyalelo enikezwa uchwepheshe wezokunakekelwa kwempilo. Njenganoma yimuphi umuthi, i-losartan ingase ibe nemiphumela engemihle engaba khona.Imiphumela emibi evamile ingase ihlanganise isiyezi, ukukhathala, ikhanda elibuhlungu, nokucasuka kwesisu.Kunconywa ukuthi ubike noma yimiphi imiphumela emibi enzima noma eqhubekayo kumhlinzeki wezokunakekelwa kwempilo.Kafushane, i-losartan iyisivimbeli se-angiotensin II se-receptor esivame ukusetshenziswa ekwelapheni umfutho wegazi ophakeme, izimo zenhliziyo ezifana nokuhluleka kwenhliziyo, kanye ne-nephropathy yesifo sikashukela.Ngokuvimbela isenzo se-angiotensin II, i-losartan isiza ukuphumula futhi yandise imithambo yegazi, ngaleyo ndlela inciphise umfutho wegazi futhi ithuthukise ukusebenza kwenhliziyo.Kuwumuthi obalulekile ekulawuleni lezi zimo futhi kufanele uthathwe njengoba uqondiswa uchwepheshe wezempilo.