o-Cresolphthalein Complexone CAS:2411-89-4 Impuphu emhlophe
| Inombolo Yekhathalogi | XD90463 |
| Igama Lomkhiqizo | o-Cresolphthalein Complexone |
| I-CAS | 2411-89-4 |
| I-Molecular Formula | I-C32H32N2O12 |
| Isisindo samangqamuzana | 636.62 |
| Imininingwane Yesitoreji | I-ambient |
| Ikhodi Yentela Evumelanisiwe | 2932209090 |
Ukucaciswa Komkhiqizo
| Ukulahlekelwa Ekumisweni | 7.23% |
| Ukubukeka | Impushana emhlophe |
| Isivivinyo | 99% |
| Izinga Lokushisa Lokugcina | +20 ° C |
| Isisindo samangqamuzana | 636.6 |
| Ukuncibilika | Sula isixazululo esinsomi |
| Izinsalela ekushiseni | 0.5% ubuningi |
| I-nitrogen | 4.1-4.7% |
| Lambda max | 573nm ku-0.1N sodium hydroxide |
| Lama Max | 575(377)nm ku-0.1 N sodium hydroxide |
| Ikhabhoni | 58-63% |
Amaprotheni e-bone morphogenetic (BMPs) adlala indima ebalulekile ekwakhekeni kwamathambo noqwanga.Kulezi zakhiwo, ama-BMP asetshenziswa emkhakheni wobunjiniyela bezicubu ukuze kunxenxe ukuvuselelwa kwamathambo ezicutshini ezilimele.Ukuze unqobe izithiyo ngenxa yokusetshenziswa kwawo wonke amaprotheni, ama-peptide okwenziwa atholakala kuma-BMP angabazali aphume njengama-molecule athembisayo okwakhiwa kwe-biomaterial.Esizeni sesakhiwo sezakhiwo zokuhlola ze-BMP-2 receptor ezibikwe ezincwadini, siklame ama-peptide amathathu, sakhiqiza kabusha isifunda se-BMP-2 esibophezelekile ekubopheni uhlobo lwe-II lwesamukeli, i-ActRIIB.Lawa ma-peptide abonakala nge-NMR, futhi izici zesakhiwo se-interface esibophayo ye-peptide-receptor zagqanyiswa ngokuhlolwa kwe-docking.Ama-affinities abophezelayo e-Peptide-receptor ahlaziywa kusetshenziswa i-ELISA kanye namasu e-surface plasmon resonance.Ngaphezu kwalokho, ukuhlolwa kwamaselula kwenziwa ukuze kuhlolwe izakhiwo zabo ze-osteoinductive.I-chimera peptide, etholwe ngokuhlanganisa ukulandelana kwe-ion port 73-92 kanye ne-30-34 ye-BMP-2, ikhombisa ukuhlobana okuhle kakhulu kwe-ActRIIB ochungechungeni futhi imele isiqalo esihle sokuklanywa kwezinhlanganisela ezintsha ezikwazi ukukhiqiza kabusha izakhiwo ze-osteogenic ze umzali BMP-2.
