I-PVP-K30 Cas: 9003-39-8 Impushana emhlophe ukuya kokuphuzi
| Inombolo Yekhathalogi | XD90232 |
| Igama Lomkhiqizo | I-PVP-K30 |
| I-CAS | 9003-39-8 |
| I-Molecular Formula | C8H15NO |
| Isisindo samangqamuzana | 141.2108 |
| Imininingwane Yesitoreji | I-ambient |
| Ikhodi Yentela Evumelanisiwe | 39059990 |
Ukucaciswa Komkhiqizo
| Amanzi | <5% |
| Izinsimbi ezinzima | <10ppm |
| pH | 3-7 |
| Izinsalela ekushiseni | <0.1% |
| Ama-aldehydes | 0.05% ubuningi |
| I-nitrogen | 11.5 - 12.8% |
| Ukubukeka | Impushana emhlophe ukuya kokuphuzi |
| K Inani | 27 - 32.4 |
| IHydrazine | 1.0% ubuningi |
| Isivivinyo | 99% |
Siphenye ukuzinza komzimba kwe-amorphous curcumin dispersions kanye nendima yokusebenzelana kwe-curcumin-polymer intermolecular ekubambezelekeni kwecrystallization.I-Curcumin iyinhlanganisela yemodeli ethakazelisayo njengoba yakha kokubili i-intra kanye ne-intermolecular hydrogen bond ku-crystal.Kwaphenywa isethi ehlukene ngokwesakhiwo yamapholymeri okuhlakazeka kwe-amorphous;i-poly(vinylpyrrolidone), i-Eudragit E100, i-carboxymethyl cellulose acetate butyrate, i-hydroxypropyl methyl cellulose (HPMC) kanye ne-HPMC-acetate succinate.I-spectroscopy ye-Mid-infrared yasetshenziselwa ukunquma nokulinganisa izinga lokusebenzisana kwe-curcumin-polymer.Ukuzinza ngokomzimba ngaphansi kwezimo ezihlukene zemvelo kwakuqashwe i-powder X-ray diffraction.Ukuzinza kwamakhemikhali e-Curcumin kwakuqashwe i-UV-Vis spectroscopy.Ukuhlukaniswa kwe-curcumin ye-amorphous ezinzile kwakunzima ngenxa yokungabikho kwama-polymers.Ama-polymers abonakale esebenza ngempumelelo i-curcumin crystallization inhibitors evumela ukukhiqizwa kwe-amorphous dispersions eqinile;noma kunjalo, ama-polymers abonise amakhono ahluke kakhulu okuvimbela i-crystallization ngesikhathi sokugcina isikhathi eside.I-Curcumin intramolecular hydrogen bonding inciphise izinga lokuhlangana kwayo kwe-hydrogen nama-polymers;yingakho ama-polymers amaningi ayengewona ama-crystallization inhibitors asebenza kahle kakhulu.Sekukonke, ama-polymers afakazele ukuthi angama-crystallization inhibitors, kodwa ukuvimbela kwakulinganiselwe ngenxa ye-intramolecular hydrogen bonding ku-curcumin, okuholela ekwehleni kwekhono lama-polymers ukusebenzisana ezingeni lamangqamuzana.
