I-Pyridoxal-5'-phosphate monohydrate CAS:41468-25-1 99% Okumhlophe kuya kumpuphu ophuzi okhanyayo
| Inombolo Yekhathalogi | XD90390 |
| Igama Lomkhiqizo | I-Pyridoxal-5'-phosphate monohydrate |
| I-CAS | 41468-25-1 |
| I-Molecular Formula | C8H10NO6P·H2O |
| Isisindo samangqamuzana | 265.16 |
| Imininingwane Yesitoreji | 2 kuya ku-8 °C |
| Ikhodi Yentela Evumelanisiwe | 29362500 |
Ukucaciswa Komkhiqizo
| Izinsimbi ezinzima | 20ppm ubuningi |
| Inani lepuleti eliphelele | 1000 cfu/g ubuningi |
| E.Coli | Okubi |
| I-Salmonella | Okubi |
| Ukulahlekelwa Ekumisweni | 10.0% ubuningi |
| I-Staphylococcus aureus | Okubi |
| Isivivinyo | 99% |
| Ukubukeka | Impushana emhlophe ekhanyayo ukuya kophuzi |
| I-Yeast & Mold Count | 100 cfu/g ubuningi |
| Usuku lokukhiqiza | I-TBC |
| I-Coliform | Okubi |
| I-Pyridoxine (HPLC) | 0.01 % ubuningi |
| PH(0.25% ag Isixazululo) | 2.6-3.0 |
Ukulungiswa okuphumelelayo kwe-myelin ku-CNS yabantu abadala kudinga ukukhiqizwa okuqinile nokufika ngesikhathi kwamaprotheni e-myelin ukuze kukhiqizwe amashethi e-myelin amasha.Izindlela zokulawula eziyisisekelo kanye nesisekelo samangqamuzana esiyinkimbinkimbi sokuvuselelwa kabusha kwe-myelin, nokho, zisalokhu zingaqondwa kahle.Lapha, siphenya indima yokusayina kwe-ERK MAP kinase kule nqubo.Ukususwa okunemibandela kwe-Erk2 kumaseli wohlu lozalo lwe-oligodendrocyte kubangele ukulibaziseka kwe-remyelination ngemva kokulimala okuqeda amandla ku-corpus callosum yegundane elidala.Ukulungiswa okubambezelekile kwenzeke ngenxa yokushoda okuthile ekuhumusheni iphrotheni enkulu ye-myelin, i-MBP.Uma ingekho i-ERK2, ukwenziwa kusebenze kwe-ribosomal protein S6 kinase (p70S6K) kanye nethagethi yayo yaphansi, i-ribosomal protein S6 (S6RP), yaphazamiseka ngesikhathi esibucayi lapho ama-oligodendrocyte e-premyelinating ayeshintshela kumaseli avuthiwe akwazi ukukhiqiza amashethi e-myelin amasha.Ngakho-ke, sichaze isixhumanisi esibalulekile phakathi kwe-ERK MAP kinase signaling cascade kanye nemishini ye-tra nslational ikakhulukazi ekubuyiseleni ama-oligodendrocyte ku-vivo.Le miphumela iphakamisa indima ebalulekile ye-ERK2 ekulawuleni ukuhumusha kwe-MBP, iphrotheni ye-myelin ebonakala ibalulekile ekuqinisekiseni isizukulwane esifike ngesikhathi samashethi e-myelin amasha kulandela ukulimala okuqeda umfutho ku-CNS yabantu abadala.
