Thiabendazole Cas: 148-79-8
Inombolo Yekhathalogi | XD92377 |
Igama Lomkhiqizo | Thiabendazole |
I-CAS | 148-79-8 |
Ifomu le-Molecularla | I-C10H7N3S |
Isisindo samangqamuzana | 201.25 |
Imininingwane Yesitoreji | I-ambient |
Ikhodi Yentela Evumelanisiwe | 29414000 |
Ukucaciswa Komkhiqizo
Ukubukeka | i-crystal powder emhlophe |
U-Asay | 99% iminithi |
I-Melting Point | 296-303°C |
Amanzi | <0.5% |
I-Thiabendazole iwumphumela we-benzimidazole owethulwa njengomuthi wezilwane ngeminyaka yawo-1960 futhi kamuva njengomuthi womuntu we-anthelminthic.Inomsebenzi obanzi we-anthelminthic osebenza ngempumelelo ezinhlotsheni ezahlukahlukene zezifo ze-nematode.Kuyi-ovicidal kanye ne-larvicidal.Iphinde isebenze kakhulu ngokumelene nesikhunta se-saprophytic kanye ne-pathogenic in vitro futhi ibonise izakhiwo zokulwa nokuvuvukala, i-antipyretic kanye ne-analgesic ezilwaneni zaselabhorethri[1].Ngokomtholampilo, isetshenziswa ngokuyinhloko ngokumelene ne-Strongyloides stercoralis kanye ne-cutaneous larva migrans.
Indlela yokwenza ayiqondakali kahle.Kuye kwaboniswa ukuvimbela i-mitochondrial fumurate reductase, eqondene ne-helminths[2].I-Thiabendazole ingase futhi ithinte ama-parasite microtubules, ngendlela efana naleyo echazwe nge-mebendazole (bona i-Mebendazole).