I-Spectinomycin dihydrochloride pentahydrate CAS:22189-32-8 I-crystaline powder emhlophe
| Inombolo Yekhathalogi | XD90369 |
| Igama Lomkhiqizo | I-Spectinomycin dihydrochloride pentahydrate |
| I-CAS | 22189-32-8 |
| I-Molecular Formula | C14H24N2O7·2HCl·5H2O |
| Isisindo samangqamuzana | 495.30 |
| Imininingwane Yesitoreji | 2 kuya ku-8 °C |
| Ikhodi Yentela Evumelanisiwe | 29419090 |
Ukucaciswa Komkhiqizo
| Isivivinyo | 99% |
| Ukubukeka | I-crystalline powder emhlophe |
Ukuphenya nge-molecular epidemiology of isolates ye-Neisseria gonorrhoeae yase-Saskatchewan, e-Canada, kusetshenziswa i-Neisseria gonorrhoeae multi antigen sequence typing (NG-MAST), kanye nokuhlola izinhlangano phakathi kokungenwa yi-antimicrobial susceptibility (AMS) kanye nezinhlobo ezithile zohlobo (STs). , eziqoqwe phakathi kuka-2003 no-2008, zabhalwa i-NG-MAST.Ama-ST aqoqwe uma enye ye-alleles yawo yayivamile futhi enye ihluke ngo-≤1% ngokulandelana kwe-DNA.I-AMS yanqunywa nge-agar dilution (CLSI) kuma-antibiotics ayisikhombisa. I-N gonorrhoeae isolate yaxazululwa yaba ama-NG-MAST STs angama-82 kanye namaqembu angu-18 e-NG-MAST ST anamaqembu angu-25, 3655, 921, 3654, 3657 kanye no-3656 ahlanganisa u-53. /320) ezindaweni ezingazodwa.I-N gonorrhoeae isolate esengozini kuwo wonke ama-antimicrobial ahloliwe ayebaluleke kakhulu (p<0.05) ehlotshaniswa ne-ST 25 (87%).Ezinye izinhlangano ezibalulekile phakathi kwe-ST ne-AMS zifakiwe: I-ST 3654 futhi ihlukanisa ngokugxila okuncane kokuvimbela i-≥0.03 mg / L kuya kwesizukulwane sesithathu se-ceph alosporins;I-ST 3711 (100%) kanye ne-TRNG;kanye ne-ST/group 3654 (43%) kanye nokumelana ne-chromosomal ku-penicillin ne-tetracycline.Ama-ST/Amaqembu amaningana e-NG-MAST ayehlotshaniswa kakhulu nama-isolate ane-chromosomal ukumelana ne-tetracycline.I-Isolates imelana ne-ciprofloxacin (n=5) kanye ne-azithromycin (n=2) ivele njenge-STs ngayinye.Ukuhlangana okubalulekile kwabonwa phakathi kwe-STs ngayinye, ubulili kanye neminyaka yesiguli, kanye nokusatshalaliswa kwesifunda nesikhashana.Izinhlangano phakathi kwe-N gonorrhoeae AMS kanye ne-NG-MAST STs zihlonziwe futhi zingase zibe usizo ekubikezeleni i-AMS esifundeni.Ngenxa yokuthi ama-ST emazweni ahlukene ahluka kakhulu, ukusetshenziswa kwe-NG-MAST ekuqaguleni kwe-AMS emhlabeni jikelele kudinga ucwaningo olwengeziwe.
