I-Vancomycin hydrochloride CAS:1404-93-9 99% Imhlophe noma i-tan to pink powder
| Inombolo Yekhathalogi | XD90370 |
| Igama Lomkhiqizo | I-Vancomycin hydrochloride |
| I-CAS | 1404-93-9 |
| I-Molecular Formula | I-C66H75Cl2N9O24.HCl |
| Isisindo samangqamuzana | 1485.72 |
| Imininingwane Yesitoreji | 2 kuya ku-8 °C |
| Ikhodi Yentela Evumelanisiwe | 29419000 |
Ukucaciswa Komkhiqizo
| Amanzi | I-NMT 5.0% |
| Izinsimbi ezinzima | I-NMT 30ppm |
| pH | 2.5-4.5 |
| Ama-bacterium endotoxins | I-NMT 0.33EU/mg ye-Vancomycin |
| Ukucaca Kwesixazululo | Kucace |
| Isivivinyo | 99% |
| Vancomycin B | I-NLT 900ug/mg |
| Umkhawulo we-monodechlorovancomycin | I-NMT 4.7% |
| Ukubukeka | Imhlophe, icishe ibe mhlophe, noma i-tan to pink powder |
Izehlakalo zezifo ezitholwa umphakathi ze-Staphylococcus aureus zimelana ne-methicillin zikhula ngesivinini esishaqisayo.Ukwelashwa okuphumelelayo ngokomlando bekuhilela ukukhishwa kwangaphambi kwesikhathi kanye nokuphathwa kwama-antibiotic.Lolu cwaningo lwenzelwe ukuhlonza ukusebenza ngempumelelo kokwelashwa okunamandla ekwelapheni izifo zezandla.Uhlolo olungahleliwe olulindelwe lwenziwa esibhedlela sesifunda se-level I.Iziguli ezinokutheleleka kwezandla zithole i-empiric intravenous vancomycin lapho zilaliswa khona noma nge-intravenous cefazolin.Imiphumela yalandelelwa kusetshenziswa ubunzima bokutheleleka, impendulo efanele yomtholampilo, kanye nobude besikhathi sokuhlala.Ukusebenza kahle kwezindleko kubalwe kusetshenziswa izindleko eziphelele zesiguli ngasinye kuwo womabili amaqembu.Ukuhlaziywa kwezibalo kwenziwa.Iziguli ezingamashumi amane nesithupha zabhaliswa ocwaningweni.Amashumi amabili nane afakwe ngokungahleliwe ku-cefazolin (amaphesenti angu-52.2) kanye nama-22 (amaphesenti angu-47.8) e-vancomycin.Kwakungekho umehluko wezibalo phakathi kwezindleko zokwelashwa (p <0.20) noma ubude besilinganiso sokuhlala (p <0.18) phakathi kwamaqembu.Iziguli ezingahleliwe ku-cefazolin zinezindleko eziphakeme zokwelashwa uma kuqhathaniswa neziguli ezingahleliwe ku-vancomycin (p <0.05).Iziguli ezinezifo ezinzima kakhulu zinezindleko ezibiza kakhulu zokwelapha (p <0.0001) kanye nobude besilinganiso sokuhlala isikhathi eside (p = 0.0002).Ngasekupheleni kocwaningo, izehlakalo ze-S. aureus emelana ne-methicillin etholwe ngumphakathi esibhedlela sesifunda sababhali zitholakale zingamaphesenti angama-72, okudale ukuthi ucwaningo lunqanyulwe ngaphambi kwesikhathi yibhodi lokubuyekeza lesikhungo ngenxa yezigameko eziningi. ngaphandle kokungahleliwe okwengeziwe.Ukwelashwa kwangaphambi kwesikhathi okufanelekile kwe-S. aureus emelana ne-methicillin akukaqinisekiswa ngokuqinisekile.Awukho umehluko emphumeleni wokusetshenziswa kwe-cefazolin ngokumelene ne-vancomycin njenge-ejenti yomugqa wokuqala ohlonziwe.
