I-Thrombin CAS:9002-04-4
| Inombolo Yekhathalogi | XD90400 |
| Igama Lomkhiqizo | I-Thrombin |
| I-CAS | 9002-04-4 |
| I-Molecular Formula | I-C6H14O6 |
| Isisindo samangqamuzana | 182.17 |
| Imininingwane Yesitoreji | 2 kuya ku-8 °C |
| Ikhodi Yentela Evumelanisiwe | 30021900 |
Ukucaciswa Komkhiqizo
| I-Melting Point | 166-168 ° C |
| Ukubukeka | Impushana emhlophe |
Izinzwa ze-PH zakhiwe ngamafilimu e-iridium oxide anodically electrodepositing iridium oxide (AEIROFs) kuma-microelectrodes kuma-chips futhi ambozwa nge-poly(ethyleneimine) (PEI) ukuze kube nokuzinza komshini.Lokhu kubonisa ukusabela kwe-super-Nernstian ku-pH ukusuka ku-pH 4.0 ukuya ku-7.7 ku-chloride-free phosphate buffer.Ingaphezulu le-chip lalimbozwe nge-fibronectin ukuze kunamathiselwe amaseli e-porcine aortic endothelial (PAECs).Amandla okusebenza enzwa ye-pH yokuqapha izinguquko ze-pH yendawo aphenywa ngokuvuselela ama-PAEC nge-thrombin.Imiphumela yethu ibonisa ukuthi i-thrombin idale i-acute extracellular acidification ye-PAECs kanye nokuqedwa kwe-fibronectin, okwenza i-pH yendawo yehle.Ukusetshenziswa kwe-PD98059, i-mitogen-activated protein kinase (MAPK) inhibitor, kunciphise i-extracellular acidification kanye nokwanda kwe-pH yendawo.Lolu cwaningo lubonisa ukuthi izinzwa zethu ze-pH zingenza kube lula ukuphenywa kwezimpendulo zamaselula ezivusa amadlingozi ngokuqapha izinguquko ze-pH zesikhathi sangempela zamaseli axhunywe kuzinzwa.
