I-4-Methylumbelliferyl-beta-D-glucopyranpside CAS:18997-57-4 Impushana Emhlophe ukuya Emhlophe 99%
Inombolo Yekhathalogi | XD90023 |
Igama Lomkhiqizo | 4-Methylumbelliferyl-beta-D-glucopyranpside |
I-CAS | 18997-57-4 |
I-Molecular Formula | I-C16H18O8 |
Isisindo samangqamuzana | 338.31 |
Imininingwane Yesitoreji | -15 kuya ku-20 ° C |
Ikhodi Yentela Evumelanisiwe | 29400000 |
Ukucaciswa Komkhiqizo
Ubumsulwa(HPLC) | iminithi 99% |
Ukujikeleza okuqondile okubonakalayo | -97 kuya ku-103° |
Ukubukeka | Impushana emhlophe ukuya kokumhlophe |
Amanzi | ubuningi 2% |
I-4-Methylumbelliferyl β-D-glucopyranoside isetshenziswe njenge-substrate: · ekuhlolweni komsebenzi we-glucosylceramidase β enzyme ezingxenyeni ezithuthukisiwe ze-lysosome ezivela kuma-primary hippocampal neurons · ku-β-glucosidase assay ngesikhathi sokuvutshelwa kwe-yeast · to assay glusebro-1GB umsebenzi ku-macrophage cell line (RAW)
I-4-Methylumbelliferyl β-D-glucopyranoside iyi-synthetic enzymatic substrate ye-glycosidase.Isetshenziswa njenge-substrate ye-β-glucosidase evela ku-enterococci.
Sibika ukuthi abanikeli be-glycoside abalula bangashintsha kakhulu ukulingana kokusabela kwe-glycosyltransferase-catalyzed, baguqule ukwakheka kwe-NDP-ushukela kusuka ku-endothermic kuya kunqubo ye-exothermic.Ukukhombisa ukusetshenziswa kwalokhu kuguquguquka kwe-thermodynamic, sigqamisa ukwakheka kwe-glycosyltransferase-catalyzed yama-nucleotide kashukela angama-22 avela kubanikeli bashukela abaphunga elimnandi, kanye nokwakheka okuhambisanayo kwe-sugar nucleotide okuhambisanayo njengamandla okushayela kumongo we-glycosyltransferase-catalyzed reactions for i-glycodiversification ye-molecule encane.Laba banikeli bephunga elimnandi baphinde bavumela ukuhlolwa kombala okuvamile kwe-glycosyltransfer, okusebenzayo ekutholweni kwezidakamizwa, ubunjiniyela bamaprotheni nolunye uphenyo oluyisisekelo oluncike ku-sugar nucleotide.Lolu cwaningo luphonsela inselelo ngokuqondile umbono ovamile wokuthi i-NDP-ushukela abanikeli bakashukela 'abanamandla amakhulu' uma bekhishwa esimeni sabo esingokwesiko sebhayoloji.