5-Fluoro-2′-deoxyuridine Cas:50-91-9
| Inombolo Yekhathalogi | XD90578 |
| Igama Lomkhiqizo | I-5-Fluoro-2'-deoxyuridine |
| I-CAS | 50-91-9 |
| I-Molecular Formula | I-C9H11FN2O5 |
| Isisindo samangqamuzana | 246.19 |
| Imininingwane Yesitoreji | 2 kuya ku-8 °C |
| Ikhodi Yentela Evumelanisiwe | 29349990 |
Ukucaciswa Komkhiqizo
| Ukubukeka | Impushana emhlophe ukuya emhlophe |
| Isivivinyo | 99% |
| Ukulahlekelwa Ekumisweni | ≤0.5% |
Ikhono leClostridium thermocellum lokucekela phansi ngokushesha i-cellulose futhi ivubele imikhiqizo eholela e-hydrolysis ibe yi-ethanol iyenza ibe ingxenyekazi ethembisayo yokukhiqizwa kwe-cellulosic biofuel ngokusebenzisa i-bioprocessing ehlanganisiwe.Nokho, okwamanje, isivuno se-ethanol singaphansi kakhulu kwesithiyori esiphezulu ngenxa yezindlela zomkhiqizo ezinamagatsha eziphambukisa ikhabhoni nama-electron aye ku-formate, i-H2, i-lactate, i-acetate, nama-amino acid ayimfihlo.Ukuze uqondise kabusha i-carbon ne-electron flux kude nefomethi, izakhi zofuzo ezifaka ikhodi ku-pyruvate:formate lyase (pflB) kanye ne-PFL-activating enzyme (pflA) zisusiwe.Ukukhiqizwa kwefomethi kuhlobo lwe-Δpfl oluwumphumela uye kwaqedwa futhi ukukhiqizwa kwe-acetate kwehle ngo-50 % kukho kokubili okuyinkimbinkimbi nesimaphakathi esichaziwe.Izinga lokukhula lohlobo lwe-Δpfl lehle ngo-2.9-fold in defined medium and biphasic growth ibonwe kokumaphakathi okuyinkimbinkimbi.Ukwengezwa kwendawo echaziwe enefomethi engu-2 mM ebuyiselwe izinga lokukhula le-Δpfl ukuya ku-80 % wobunzima bomzali.Indima ye-pfl kumasu wobunjiniyela be-metabolic kanye ne-C1 metabolism kuyaxoxwa ngayo.
