Imikhiqizo

I-L-(-)-fucose iphinde ibe nokusetshenziswa okuhlukahlukene emkhakheni wezimonyo, isibonelo njengendawo yokuthambisa isikhumba, isivuseleli sesikhumba kanye ne-ejenti elwa nokuguga, noma ukuvimbela ukuvuvukala kwe-epidermal (isikhumba).

I-L-(-)-fucose ilawula ukusebenza kwamaseli e-Treg emathunjini ngokulawula impendulo yokuzivikela komzimba yamaseli e-DC, futhi ilawula ukukhiqizwa kwe-bile acids ezimbali zamathumbu.Phakathi naleso sikhathi, i-L-(-)-fucose ingavimbela ukufinyela kwemisipha yamathumbu kanye ne-spasm ngokulawula i-nNOS.I-L-(-)-fucose ingahlangana namagciwane, amabhaktheriya kanye nobuthi ukuze kuvinjwe ukuthi zingatheleli amangqamuzana, ngaleyo ndlela kuthuthukise ukumelana nomzimba.Ocwaningweni nasekuthuthukisweni kwemithi emisha ehloselwe ukulwa nomdlavuza, ubuchwepheshe be-CarboConnect okwamanje busetshenziswa kuma-antibody-drug conjugates (ADCs) kanye nama-extracellular drug conjugates (EDCs), okwamanje asebenza ocwaningweni lwamazwe ngamazwe futhi enze impumelelo enkulu.Ama-antibody nezidakamizwa kuxhunywe kanye neqembu le-amino L-(-)-fucose ukuze kuhlolwe umsebenzi wezidakamizwa ohlukile.I-L-(-)-fucose ingenye ye-8 ushukela obalulekile emzimbeni womuntu futhi enye ye-oligosaccharides obisini lwebele lomuntu (ubisi lwebele lomuntu luqukethe i-sialic acid, i-N-acetylglucosamine, i-D-glucose ne-D-galactose, njll. ), okuyizithako zokudla ezifanele kanye nezithako zokudla kanye nezici ezithuthukisa amasosha omzimba ekudleni kwezingane.

I-L-(-) -I-Fucose, uhlobo lukashukela we-hexose, idlala indima ekunqumeni kwesakhiwo se-antigen subtype yeqembu legazi le-AB, i-electin-mediated leukocyte endothelial adhesion, kanye nokusebenzisana kwe-host-microbe.