I-Nicotinamide Cas: 98-92-0 Impushana emhlophe
| Inombolo Yekhathalogi | XD90447 |
| Igama Lomkhiqizo | I-Nicotinamide |
| I-CAS | 98-92-0 |
| I-Molecular Formula | I-C6H6N2O |
| Isisindo samangqamuzana | 122.12 |
| Imininingwane Yesitoreji | I-ambient |
| Ikhodi Yentela Evumelanisiwe | 29362900 |
Ukucaciswa Komkhiqizo
| Ukubukeka | Impushana emhlophe |
| Isivivinyo | 99% |
| Izinsimbi ezinzima | 128°C ~ 131°C |
| Ukuhlonza | Okuhle |
| pH | 6.0 ~ 7.5 |
| Ukulahlekelwa Ekumisweni | ≤0.5% |
| Ukuncibilika | Kuyavumelana |
| Umlotha one-sulphate | ≤0.1% |
| Ukucaca Kwesixazululo | Kucace |
| Insimbi Enzima | ≤0.003% |
Ngaphambilini sasungula isiko lesikhathi eside, le-3-dimensional of organoid kusuka ezicutshini zegundane (amathumbu, isisu, amanyikwe, nesibindi) kanye namathumbu omuntu namanyikwe.Lapha sichaza izimo ezidingekayo zesiko lesikhathi eside le-3-dimensional of human gastric stem cells.Ubuchwepheshe bungasetshenziswa ukutadisha impendulo ye-epithelial ekuthelelekeni nge-Helicobacter pylori.Sikhiqize ama-organoid kusuka kumasampula okuhlinzwa e-human gastric corpus.Izimo zesiko zathuthukiswa ngokusekelwe kulezo ze-mouse gastric kanye nezinhlelo zamathumbu omuntu.Sisebenzise i-microinjection ukuthelela ama-organoid nge-H pylori.Izimpendulo ze-Epithelial zikalwe kusetshenziswa i-microarray kanye ne-quantitative polymerase chain reaction analysis.Amaseli e-gastric omuntu anwetshwa ngokungenamkhawulo kumasiko we-3-dimensional.Sakha amaseli kusuka ezicutshini zesisu ezinempilo, ama-stem cells ahlungwe olulodwa, noma izicubu zesimila.Ama-Organoid agcine izici eziningi zezicubu zawo ngokulandelana kwawo ngokususelwa kumlando wawo, ukuvezwa komaka, kanye ne-euploidy.Ama-Organoid avela ezicutshini ezinempilo aveze omaka bemigqa emi-4 yesisu futhi azihlelele ezizindeni zendlala nomgodi.Angase aqondiswe ukuze aveze ngokuqondile noma yiziphi izigaba zendlala yesisu, noma umgodi wesisu, ngokwengeza i-nicotinamide nokuhoxiswa kwe-WNT.Nakuba imigqa yemigodi yesisu yayinokusabela okuncane kuphela ekuthelelekeni kwamagciwane, imigqa ye-gastric gland yaphakamisa impendulo enamandla yokuvuvukala.Lolu hlelo lungasetshenziswa ukufunda ukutheleleka nge-H pylori kanye nezinye izifo zesisu.Copyright © 2015 AGA Institute.Ishicilelwe ngabakwa-Elsevier Inc. Wonke amalungelo agodliwe.
