I-Nystatin dihydrate CAS: 1400-61-9 Nystatin A1>85%;noma yiziphi ezinye izinhlanganisela
| Inombolo Yekhathalogi | XD90352 |
| Igama Lomkhiqizo | I-Nystatin dihydrate |
| I-CAS | 1400-61-9 |
| I-Molecular Formula | C47H75NO17 · 2H2O |
| Isisindo samangqamuzana | 962.10 |
| Imininingwane Yesitoreji | -15 kuya ku-20 ° C |
| Ikhodi Yentela Evumelanisiwe | 29419000 |
Ukucaciswa Komkhiqizo
| Isiphetho | Ihambisana ne-Ph.Eur.9.7 |
| I-Pseudomonas aeruginosa | Akekho |
| pH | 6.0-8.0 (3% isixazululo esinamanzi) |
| Isivivinyo | I-Nystatin A1>85%;noma yiziphi ezinye izinhlanganisela <4% |
| Ukulahlekelwa Ekumisweni | <5.0% |
| Ukubukeka | Impushana ephuzi noma ensundu |
| Umlotha one-sulfate | <3.5% |
| Ukuhlolwa kwe-ID D | Ivumelana (UV) |
| I-TAMC | <1000cfu/g |
| I-TYMC | <100cfu/g |
| I-Staphylococcus Aureus | Akekho |
| I-Residual Solvent Methanol | <3000ppm |
| I-Mesityloxide | <500ppm |
| I-Residual Solvent | <5000ppm |
| I-Identification (UV) Test A | efanayo nereferensi |
| I-Absorbance A305 | >0.6 |
| i-bile-tolerant gram-negative bacteria (E.coli + Salmonella sp.) | Akekho |
| Izinhlobo zeClostridia | Akekho |
| Izincibilikisi Ezisele (1-butanol) | <1000ppm |
| Ukuhlanzeka;I-Microbial Assay | I-NLT>4400 IU/mg ngokomisiwe |
Ukunquma okuguquguqukayo komtholampilo ukuhlukanisa i-invasive pulmonary aspergillosis (IPA) kusuka kukholoni ezigulini ezine-pneumopathies ezingapheli ezinesiko elihle le-Aspergillus spp.kumasampula okuphefumula.Ucwaningo lweqembu le-Retrospective kuhlanganise neziguli ezinezihlukaniso zokuphefumula ze-Aspergillus spp.phakathi nenkathi yeminyaka eyi-10.I-IPA yahlolwa ngokuya ngemibandela ye-Bulpa.Kwaqoqwa okuguquguqukayo komtholampilo futhi kwenziwa ukuhlaziywa kokuhlehliswa kwezinto eziningi.Iziguli ezingamashumi ayisishiyagalombili nantathu ezinokuhlukaniswa kwe-Aspergillus spp.kusuka kumasampula okuphefumula afakiwe;Amaphesenti angu-68.7 (n=57) eziguli ayenesifo esingamahlalakhona sokuvinjwa kwamaphaphu, i-18% (n=15) i-pulmonary fibrosis kanye ne-13.3% (n=11) i-asthma ye-bronchial.Iziguli ezingamashumi amabili nambili (26.6%) zine-IPA.Ukusetshenziswa kwe-fluconazole (NOMA 4.49; CI 95% 1.5-13.4; P=.007), ukwehluleka kokuphefumula okukhulu (NOMA 4.64; CI 95% 1.46-14.72; P=.009) kanye nesikhathi sokulaliswa esibhedlela (NOMA 1.05; CI 95% 1.01-1.1; P=.006) zazihlotshaniswa ne-IPA.Ukusetshenziswa kwangaphambili kwe-fluconazole, ukwehluleka ukuphefumula okukhulu kanye nesikhathi sokulaliswa esibhedlela kuhlotshaniswa ne-IPA ezigulini ezine-pneumopathies engapheli ezinokuhlukaniswa kokuphefumula kwe-Aspergillus spp.Copyright © 2012 Elsevier España, SL Wonke Amalungelo agodliwe
