Imikhiqizo

I-Trityl candesartan iyisidakamizwa esaziwa nangokuthi i-candesartan tert-butyl ester.Kuyinhlanganisela eyandulela ye-candesartan cilexetil, esetshenziselwa ukwenza i-candesartan cilexetil.I-Candesartan cilexetil iyi-angiotensin II receptor antagonist esetshenziswa kabanzi ekwelapheni umfutho wegazi ophakeme kanye nokwehluleka kwenhliziyo.Isebenza ngokuvimbela umsebenzi wama-angiotensin II receptors, ukwehlisa umfutho wegazi, ukunciphisa umthwalo wenhliziyo, nokukhuthaza i-vasodilation.Ukusetshenziswa okuyinhloko kwe-Trityl candesartan ekuthuthukisweni kwamalungiselelo emithi kufana nokuphakathi kokuhlanganiswa kwe-candesartan cilexetil.Ihlangana nezinye izandulela ze-candesartan cilexetil ukukhiqiza i-candesartan cilexetil, esetshenziswa ekulungiseni imikhiqizo yezemithi.Kumele kuqashelwe ukuthi i-trityl candesartan ngokwayo ayisona isidakamizwa esiphezulu sokwelapha, kodwa iyinhlanganisela eyinhloko yokulungiswa kwe-candesartan cilexetil.Ukusetshenziswa okuqondile kanye nezicelo kuncike ocwaningweni nasekuthuthukisweni kwezidingo zamalungiselelo emithi.Noma yimuphi umsebenzi osebenzisa noma ophatha amakhemikhali kufanele ulandele izinqubo zokuphepha ezifanele kanye nemihlahlandlela yaselabhorethri.