Imikhiqizo

I-Vancomycin hydrochloride iyi-antibiotic ye-glycopeptide futhi ingusawoti we-hydrochloride we-vancomycin.Imhlophe noma imhlophe njenge-crystalline powder ezingeni lokushisa legumbi.Indlela yokusebenza kwayo ukuthi ingabopha ngokusondelana okuphezulu ku-poly-terminus alanyl-alanine ye-peptide eyandulelayo ebekwe odongeni lweseli amangqamuzana ebhaktheriya azwelayo, ivimbe i-biosynthesis ye-peptide glycan polymer eyakha udonga lwamaseli ebhaktheriya, futhi ngaleyo ndlela. okuholela ekukhubazekeni kodonga lwamaseli nokuqhubeka nokubulala amagciwane.Ngaphezu kwalokho, kungenzeka futhi ukuguqula ukufinyeleleka kwe-bacterial cell membrane, futhi ngokukhetha ukuvimbela ukuhlanganiswa kwe-RNA.Isici se-vancomycin hydrochloride umphumela wayo oqinile wokubulala amagciwane ngokumelene namagciwane e-Gram-positive afana ne-Staphylococcus aureus, i-Staphylococcus epidermidis, i-Streptococcus pyogenes, ne-streptococcus pneumoniae.Iphinde ibe nemiphumela ethile yokulwa namagciwane ku-Streptococci anaerobius, Clostridium difficile, Bacillus anthracis, Actinomycetes, Corynebacterium diphtheria, Neisseria gonorrhoeae, Streptococcus viridans, Streptococcus bovis, kanye ne-Streptococcus faecalis.Kodwa-ke, kuma-bacterium amaningi e-Gram-negative, i-Mycobacterium, i-Rickettsia genus, i-Chlamydia noma isikhunta, ayivumelekile.Isebenza ngokomtholampilo ekwelapheni ukutheleleka okubangelwa yi-Staphylococcus aureus emelana ne-methicillin namanye amagciwane: i-sepsis, i-endocarditis, i-osteomyelitis, i-arthritis, ukulimala kokusha, ukuhlukumezeka kokuhlinzwa nokunye ukutheleleka kwesibili okungaphezulu, inyumoniya, ithumba lamaphaphu, i-empyema, i-peritonitis, i-meningitis, i-pseudomembranous colitis, izifo zesikhumba nezicubu ezithambile.Kuwukukhetha okuyinhloko ezigulini ezingazwani ne-penicillin futhi ezihlushwa i-enterococcal endocarditis kanye ne-Corynebacterium (class diphtheria sp) endocarditis.