Imikhiqizo

I-4''-Propyl-3-fluorobiphenyl-4-boronic acid, eyaziwa nangokuthi (4-propyl-3-fluorophenyl)boronic acid, iyinhlanganisela yamakhemikhali ethole ukusetshenziswa okubalulekile emikhakheni eyahlukene, okuhlanganisa i-organic synthesis, isayensi yezinto zokwakha, kanye nocwaningo lwezemithi.Olunye lwezinhlelo zokusebenza eziyinhloko ze-4''-Propyl-3-fluorobiphenyl-4-boronic acid isenguqukweni yokusabela kokuhlangana kwe-metal-catalyzed.Lesi sakhiwo singasebenza njenge-boronic acid block block, evumela ukwakheka kwe-carbon-carbon noma i-carbon-heteroatom bond.Isibonelo, ingasetshenziswa ku-Suzuki-Miyaura-cross-coupling reactions, lapho isabela nge-aryl noma i-vinyl halide ngaphansi kwe-palladium catalysis ukuze ikhiqize izinhlanganisela ze-biaryl.Lokhu kuhlangana kwe-cross-coupling kusetshenziswa kabanzi ekuhlanganisweni kwama-molecule ayinkimbinkimbi, okuhlanganisa imithi, amakhemikhali ezolimo, nezinto zokwakha.Ukuba khona kwe-athomu ye-fluorine ku-4''-Propyl-3-fluorobiphenyl-4-boronic acid kuthuthukisa isimo sayo esiphunga elimnandi futhi inikeza amathuba ayingqayizivele okuthuthukiswa kwezinto zokusebenza.Ukushintsha i-fluorine kungaba nomthelela omkhulu ezimpahleni ze-physicochemical ye-molecule, njengokusatshalaliswa kwayo ngogesi kanye ne-hydrophobicity.Lezi zakhiwo zenza okuphuma ku-4''-Propyl-3-fluorobiphenyl-4-boronic acid kube usizo ezinhlelweni ezihlukahlukene, njengamakristalu anguketshezi, ama-OLED (ama-organic light-emitting diode), namanye amadivaysi kagesi.Ngaphezu kwalokho, iqembu le-propyl ku ukwakheka kwe-4''-Propyl-3-fluorobiphenyl-4-boronic acid kuvumela ukukhishwa kalula, okuhlinzekela ukufinyelela ezinhlobonhlobo zokuphuma kokunye okusebenzayo.Lokhu kuvumelana nezimo kuvumela ukuhlanganiswa kwezinhlanganisela ezihlukahlukene ezinezakhiwo ezihambisanayo nokusebenza.Lokhu okuphuma kokunye kungabuye kulungiswe noma kuhlanganiswe nezinhlaka ezinkulu zamangqamuzana ukuze kwakhiwe izakhiwo eziphilayo eziyinkimbinkimbi, ama-molecule e-bioactive, nezinto ezithuthukisiwe.Ocwaningweni lwezemithi, i-4''-Propyl-3-fluorobiphenyl-4-boronic acid kanye nokuphuma kwayo kuye kwahlolisiswa njenge abangase bakwazi ukuthola izidakamizwa.Amakhompiyutha ane-fluorinated ngokuvamile abonisa ukuzinza okuthuthukisiwe kwe-metabolic, ukwanda kwe-lipophilicity, kanye nomsebenzi oshintshile wezinto eziphilayo uma kuqhathaniswa nozakwabo abangenayo i-fluorinated.Ngakho-ke, ukwethulwa kwe-athomu ye-fluorine kuma-athomu asebenza ngebhayoloji kungathuthukisa izici zabo zemithi, njengamandla kanye nokukhetha.Ekuphetheni, i-4''-Propyl-3-fluorobiphenyl-4-boronic acid inokubaluleka okukhulu njengengxenye emaphakathi ku-organic synthesis. , isayensi yezinto zokwakha, nocwaningo lwezemithi.Ikhono layo lokubamba iqhaza ekushintsheni kokuhlangana kwe-metal-catalyzed, izici eziyingqayizivele ezihlobene nokushintshwa kwe-fluorine, namandla okuphuma kokunye kuyenza ibe ithuluzi elibalulekile ekukhiqizeni ama-molecule e-organic ayinkimbinkimbi, izinto ezisebenzayo, kanye nabantu abangase bakhethe izidakamizwa.