I-Trypan Blue Cas: 72-57-1 Okumnyama okuluhlaza ngokunsundu ukuya kumpushana omnyama
| Inombolo Yekhathalogi | XD90542 |
| Igama Lomkhiqizo | I-Toluidine blue O |
| I-CAS | 92-31-9 |
| I-Molecular Formula | I-C15H16ClN3S |
| Isisindo samangqamuzana | 305.82 |
| Imininingwane Yesitoreji | I-ambient |
Ukucaciswa Komkhiqizo
| Ukubukeka | Impushana eluhlaza okwesibhakabhaka |
| Isivivinyo | 99% |
Kuyaziwa ukuthi i-Staphylococcus aureus isengozini yokungasebenzi kwe-photodynamic ngokujwayelekile, kodwa umehluko obalulekile phakathi kwezinhlobo ezithile zempendulo yokwelashwa ukhona.Nokho, izici ezinquma isenzakalo esibukiwe zihlala zingacacile.Lolu cwaningo lwaluhloselwe ukuhlola umphumela we-PDI wezinzwa ezimbili (i-protoporphyrin diarginate ne-toluidine eluhlaza okwesibhakabhaka O) ngokumelene nomtholampilo kanye nezinhlobo zereferensi ze-S. aureus.Imiphumela etholiwe ibonisa ukuthi i-isolate efanayo ingase ibonakale njengengazweli kakhulu noma izwela kakhulu ku-PDI ngokuya ngesizwali esisetshenzisiwe.Ngaphezu kwalokho, i-ejenti efanayo eqwashisa abantu ingase isetshenziselwe ngempumelelo ukuqeda ngokuphelele ezinye izinto ezingazodwa futhi ingase ingasebenzi kahle esimweni sezinye izinhlobo.Ukwengeza, ngokushintsha i-photosensitizer, siyakwazi ukuhlehlisa i-PDI "resistant" phenotype ibe "ezwelayo".Ngakho, umuntu angaphetha ngokuthi ukwenza izithombe kusebenze okubandakanya ama-ejenti amaningana azwelayo kanye nezihlukanisi ezimbalwa zezinhlobo zebhaktheriya ezifanayo kufanele kwenziwe ukuze ukungasebenzi kwe-antimicrobial photodynamic kuthembeke.Copyright © 2012 Elsevier BV Wonke amalungelo agodliwe.
